Join our Mission to Protect Humankind!
Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.
WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:
*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.
*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to p…
What you'd do
- Contribute to method development, optimization, and qualification/validation readiness activities.
- Design and execute experiments to evaluate critical method parameters and define appropriate system suitability and control strategies.
- Troubleshoot assay and instrument performance issues using a structured approach; interpret data to identify likely root causes, implement corrective actions, and document outcomes and recommendations.
- Support and/or execute method transfer activities, including protocol preparation, training support, execution at receiving labs, and resolution of transfer issues.
- Author and revise analytical methods, SOPs, protocols, and technical reports; ensure clear documentation of experimental rationale, results, and conclusions for internal review and stakeholder communication.
- Partner effectively with cross-functional teams to define analytical plans, meet project timelines, and deliver high-quality outputs.
- Communicate experimental progress and data interpretation to direct team members and project leads; flag emerging risks for senior review.
- Contribute to a compliant, safety-focused, and scientifically rigorous lab culture, model good documentation practices and data integrity expectations.
- May assist in orienting new team members to assays and workflows under the direction of senior staff (role does not carry any formal supervisory accountability).
- Perform routine and non-routine analytical testing using modern analytical methods (e.g., HPLC/UPLC, SEC, CE, UV-Vis, ELISA, electrophoresis, plate-based assays, and other biochemical/biophysical techniques).
What they want
- Strong hands-on experience with multiple analytical techniques, such as liquid chromatography (H/UPLC) and/or mass spectrometry (LC-MS), CE, SDS-PAGE, icIEF, enzyme kinetics, colorimetric and fluorescent plate-based assays, ELISA, Western Blot, and PCR.
- Experience independently driving method development or optimization activities preferred.
- Strong knowledge of analytical chemistry/biochemistry principles with demonstrated application to assay development and control strategies.
- Proven ability to independently troubleshoot non-routine assay and instrument issues using structured root-cause analysis and data-driven decision making.
- Proficient with analytical software, data processing workflows, and statistical tools.
- Strong scientific judgment and attention to detail consistently produces high-quality, inspection-ready documentation.
- Plan and prioritize work, coordinate with management and the lab team, and support meeting tight timelines.
- Clear and effective written and verbal communication; able to summarize complex data, present recommendations, and collaborate across functions.
- Ability to work in a laboratory environment for extended periods.
- Ability to lift up to 25 lbs.