Company Overview:
Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs.
What you'd do
- Maintain and culture mammalian cell lines for mRNA expression studies.
- Perform transfection experiments to evaluate mRNA constructs with different sequence designs and chemical modifications.
- Conduct protein expression and other biochemical assays to characterize mRNA performance.
- Analyze and interpret experimental results using appropriate data analysis tools.
- Process and evaluate multiple samples with careful attention to accuracy, consistency, and documentation.
- Collaborate with other teams to support cell-based editing and mRNA evaluation studies.
- Maintain detailed documentation of experiments in the ELN system.
- Adhere to all laboratory safety requirements and procedures.
- Contribute to molecular cloning, DNA preparation, and in vitro transcription (IVT) experiments as needed.
What they want
- Pursuing a BS or MS in Biological Sciences or a related field (Bioengineering, Biochemistry/Biophysics, Cell Biology/Molecular Biology, or similar).
- At least one year of relevant hands-on laboratory experience.
- Experience with mammalian cell culture and aseptic technique.
- Experience with mammalian cell transfection and cell-based assays.
- Strong attention to detail and ability to perform repetitive experimental workflows with consistency and accuracy.
- Proficient in Excel, PowerPoint, and data analysis.
- Experience maintaining a laboratory notebook and following written protocols.
- Highly motivated to learn, with a collaborative mindset, strong organizational skills, and effective communication skills.
- Applicants must be currently enrolled in a degree-granting college or university program and maintain their student status throughout the duration of the co-op.